Renin, Plasma (Plasma Renin Activity)

CPT: 84244

Synonyms

Plasma Renin Activity

Expected Turnaround Time

2 - 5 days

Specimen Requirements


Specimen

EDTA plasma

Volume

2 mL

Minimum Volume

0.4 mL (Note: This volume does not allow for repeat testing.)

Container

Lavender-top (EDTA) tube

Collection

Use EDTA plasma only! Strictly frozen. Collect 4 mL of blood in lavender-top venipuncture tube. Mix gently by inversion. Centrifuge immediately after collection. Separate and freeze plasma immediately. Please note whether recumbent or upright sample.

Storage Instructions

Store and ship frozen in plastic vial.

Test Details


Methodology

Liquid Chromatography/Mass Spectrometry (LC/MS-MS)

Reference Interval

Age Range (ng/mL/h) 0 - 11 months 2.000 - 37.000 1 - 3 years 1.700 - 11.200 4 - 5 years 1.000 - 6.500 6 - 10 years 0.500 - 5.900 11 - 15 years 0.500 - 3.300 >15 years 0.167 - 5.380 Dietary sodium levels during this period prior to testing can affect renin levels. Sodium restriction tends to cause an increase in renin activity, while supplementation can result in lower values.